Swiss biotech firm TissueLabs has launched its most superior bioprinter but, the TissuePro. Constructed for tissue engineering and regenerative medication, the brand new machine options exact multi-material printing, extra automation, and higher flexibility in comparison with the corporate’s earlier fashions.
TissuePro builds on the success of TissueStart, the corporate’s entry-level bioprinter utilized in over 300 labs throughout greater than 30 international locations. Whereas TissueStart opened the door for researchers coming into the bioprinting area, TissuePro is supposed for labs able to scale up and sort out advanced tissue fashions, organ-on-a-chip techniques, vascularized constructs, and different superior functions.
“TissuePro is all the things we’ve discovered, reinvented, and reimagined,” stated Dr. Gabriel Liguori, Founder and CEO of TissueLabs. “For those who beloved TissueStart, prepare. You’re about to fall in love once more.”
Precision Printing, Reinvented
On the coronary heart of TissuePro is TissueLabs’ proprietary Mixtrusor know-how, which lets the machine combine and print a number of bioinks on the identical time. It makes use of 5 separate piston-based extruders to present researchers very exact management (down to simply 0.1 microliters). This can be a massive enchancment over pressure-based techniques, which usually require fixed adjustment.
Based on the corporate, this setup lets researchers print advanced, detailed tissues with completely different layers and supplies. It additionally helps superior printing strategies, corresponding to coaxial and triaxial printing (methods that permit a number of bioinks to be printed in layers inside a single strand), making it simpler to recreate advanced tissue buildings just like these within the human physique. With this setup, customers can create extremely detailed, heterogeneous tissues with layered buildings and compositional gradients.
TissueLabs’ TissuePro bioprinter. Picture courtesy of TissueLabs.
To make it much more versatile, TissuePro comes with a light-curing system that makes use of 5 completely different wavelengths, permitting it to work with many varieties of supplies. Each the printheads and the print mattress may be heated or cooled (from 4°C to 60°C), so the machine works with all the things from lab-made supplies to pure ones. The system additionally consists of automated multi-head printing, which cuts down on guide work and helps labs get extra constant, repeatable outcomes.
TissuePro was developed with a variety of functions in thoughts. Whereas its core energy lies in regenerative medication, the system can also be geared towards drug improvement, most cancers analysis, organ-on-a-chip fashions, cultured meat manufacturing, and gentle robotics: fields that want precision, repeatability, and materials flexibility. The system is now obtainable for pre-order, with shipments anticipated to start in August 2025.
TissueLabs Founder and CEO Gabriel Liguori, with the TissueStart bioprinter. Picture courtesy of TissueLabs.
From Brazil to Switzerland
The launch of TissuePro additionally exhibits how a lot the corporate has grown. Initially based in Brazil, TissueLabs moved its headquarters to Switzerland to be nearer to Europe’s biotech and innovation hubs.
Underneath the management of Liguori, a surgeon-turned-entrepreneur, TissueLabs has expanded its product lineup, which now consists of extrusion and light-based bioprinters, biomaterials, and software program instruments. With TissuePro, TissueLabs is doubling down on its mission: to hurry up the trail to lab-grown tissues and organs, and put superior bioprinting instruments into the palms of extra researchers all over the world.
TissueLabs’ TissuePro bioprinter. Picture courtesy of TissueLabs.
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