A analysis crew from NIT Rourkela has created a bioink for 3D bioprinting of bone-like buildings. Led by Prof. Devendra Verma, the crew developed a composition of chitosan, gelatin, and nanohydroxyapatite that mimics pure bone properties. The analysis has been revealed within the Journal of Biomaterials Science and Carbohydrate Polymers, with a patent (No. 562791) granted in March 2025.
The bioink addresses limitations in conventional bone restore strategies like grafting and metallic implants. Not like standard bioinks that require prolonged lab preparation, this formulation stays liquid at room temperature and transforms right into a gel when uncovered to physique temperature and pH. This property permits direct utility to harm websites with out separate printing and implantation procedures.
“This analysis contributes to the rising subject of 3D bioprinting by providing a bioink that’s completely pure, straightforward to use, and able to supporting bone regeneration,” mentioned Prof. Verma. The bioink accommodates specialised nanofibers that improve cell attachment and proliferation in the course of the therapeutic course of.
The Division of Well being Analysis, Authorities of India, has supplied funding for this mission. The bioink exhibits potential for treating massive bone defects from accidents, infections, or surgical procedures, with specific relevance for reconstructive surgical procedures of the cranium and face the place exact bone restore is required.
The analysis crew, which incorporates students Tanmay Bharadwaj and Shreya Chrungoo, plans to check the bioink in animal fashions. They purpose to develop a scalable manufacturing course of in a Good Manufacturing Practices facility for future scientific trials. To help commercialization efforts, the researchers have established a startup known as Quixotix Bioprinting.
Supply: expresshealthcare.in
